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Detailed Programme

The Final programme as a pdf file is available here.


Thursday, June 27, 2019

13:00–19:00
Registration
15:00–15:30
Opening of the Meeting
Moderator: Dr. Radim Nencka
15:30–16:15
PL-1
Prof. Michal Hocek: Substituted or hetero-fused 7-deazapurine nucleoside cytostatics with complex mechanism of action
16:15–16:45
KL-1
Assoc. Prof. Izidor Sosič: Development of non-peptidic and subunit-selective inhibitors of immunoproteasome
16:45–17:30
PL-2
Prof. Jakub Fichna: Challenges in design of novel treatment options in inflammatory bowel diseases employing gold and silver
17:30–18:00
KL-2
Dr. Zlatko Janeba: Development of polysubstituted pyrimidines as potent inhibitors of prostaglandin E2 production
18:00–19:30
Welcome Cocktail


Friday, June 28, 2019

Moderator: Prof. Sanja Tomič
09:00–09:45
PL-3
Prof. Szilvia Bősze: Cargo-dependent mode of drug uptake with improved efficacy and bioavailability: the design and evaluation of target cell selective transporters and drug-conjugates
09:45–10:15
KL-3
Dr. Theodora Calogeropoulou: Constrained miltefosine derivatives. The journey towards NMT-A2, a new drug lead for visceral leishmaniasis
10:15–10:45
Coffee break
Moderator: Prof. Szilvia Bősze
10:45–11:30
PL-4
Assoc. Prof. Janez Ilaš: Inhibitors of topoisomerases: from antibacterial to anticancer agents
11:30–12:00
KL-4
Dr. Zsuzsa Baranyai: Synthesis and in vitro biological evaluation of drug-peptide conjugates against glioblastoma
12:00–12:30
KL-5
Assoc. Prof. Angeliki Kourounakis: Morpholine: A privileged scaffold for the development of multi-target bioactive molecules
12:30–13:45
Lunch
13:45–15:00
Poster Session I (odd numbers)
Moderator: Prof. Gabriele Costantino
15:00–15:45
PL-5
Prof. Sanja Tomić: The Role(s) of Dipeptidyl Peptidase III in Humans
15:45–16:15
KL-6
Prof. Michael Schnürch: Leoligin-inspired Synthetic Lignans with Selectivity for Cell-type and Bioactivity, Relevant for Cardiovascular Disease
16:15–16:45
Coffee break
Moderator: Assoc. Prof. Janez Ilaš
16:45–17:30
PL-6
Prof. Gabriele Costantino: Chasing target essentiality in the search for new antibacterials
17:30–18:00
KL-7
Assoc. Prof. Martina Hrast: Covalent warheads as new MurA inhibitors
18:00–18:20
L-1
Miriam Girardini: Characterizing a new series of efflux-pumps inhibitors as potential anti-tubercular adjuvants
18:20–18:40
L-2
Prof. Barbara Nawrot: Nanostructured conjugates of DNA oligonucleotides and boron clusters as potential dual-action anti-EGFR therapeutic nucleic acids
19:30–22:30
Congress dinner


Saturday, June 29, 2019

Moderator: Prof. Michal Hocek
08:30–09:30
Invited lecture
Dr. Tomas Cihlar: Discovery and Development of Antiviral Therapeutics for Emerging and Neglected Viral Infections
09:30–10:00
KL-8
Dr. Jose Miguel Ferreira de Oliveira: Regulation of cyclin and cyclin-dependent kinase expression by 3’,4’-dihydroxyflavonol in human in vitro models
10:00–10:30
Coffee break
Moderator: Prof. Danijel Kikelj
10:30–11:15
PL-7
Assoc. Prof. Manolis Fousteris: New artemisinin hybrid molecules with antileukemic and antimalarial activities
11:15–11:45
KL-9
Assoc. Prof. Zrinka Rajić: Harmicines as novel antiplasmodial leads
11:45–12:15
KL-10
Prof. Tibor Kurtan: Bioactive benzene-condensed heterocycles
12:15–13:15
Lunch
13:15–14:30
Poster session II (even numbers)
Moderator: Assoc. Prof. Vittorio Pace
14:30–15:15
PL-8
Prof. Yoel Rodríguez: In silico Design of Chemical Modulators for Chromatin Biology
15:15–15:45
KL-11
Dr. Lars Richter: Time is running – Large scale matched molecular pair analysis to domesticate binding kinetics
15:45–16:15 L-3 Dr. David Peralta: Why Was My Paper Rejected? Tips from an Editor on How to Get Published
16:15–16:35
Coffee break
Moderator: Prof. Yoel Rodríguez
16:35–17:20
PL-9
Assoc. Prof. Vittorio Pace: Building-up molecular complexity with carbenoids: New vistas in homologation chemistry
17:20–17:50
KL-12
Dr. Magdaléna Májeková: Targeting SERCA through drug design
17:50–18:10
L-4
Assoc. Prof. Diego Muñoz-Torrero: A novel class of chroman-based multitarget anti-Alzheimer hybrids: design, synthesis, in vitro profiling and in vivo proof-of-concept


Sunday, June 30, 2019

Moderator: Prof. Martin Doležal
09:00–09:30
KL-13
Dr. Ana Amić: Anthraquinones as potential free radical scavengers and P-glycoprotein inhibitors
09:30–10:00
KL-14
Dr. Lucia Kováčiková: Isosteric replacement brought markedly improved selectivity of aldose reductase inhibitors
10:00–10:30
KL-15
Dr. Jan Zitko: Structural modifications of pyrazinamide – rational design towards new potential anti-microbial compounds
10:30–10:50
L-5
Dr. Muhammed İhsan Han: Design, synthesis and biological activity evaluation of aryl-sulfonylthiosemicarbazides as antiproliferative agents and COX-2 inhibitors
10:50–11:20
Coffee break
Moderator: Dr. Jan Zitko
11:20–11:50
KL-16
Prof. Agostino Marrazzo: From haloperidol to new selective sigma receptor ligands
11:50–12:20
KL-17
Dr. Anna Wieckowska: Serotonin 5HT-6 receptor antagonists and cholinesterase inhibitors with Aβ antiaggregation properties in the development of multifunctional ligands against Alzheimer´s disease
12:20–12:40
L-6
Belgin Sever: New pyrazoline derivatives clubbed with thiazole scaffold as anticancer agents targeting EGFR
12:40–13:00
L-7
Dr. Constantin Tanase: New carbocyclic nucleoside analogues with an optically active substituted bicyclo[2.2.1]heptane fragment as a glycoside moiety linked to the base by a methylene group
13:00–13:30
Winning Posters Flash presentations
13:30–14:00
Closing

 

MEETING SECRETARIAT
GUARANT International spol. s r. o.
Na Pankráci 17, 140 21  Prague 4, Czech Republic
Phone: +420 284 001 444, Fax: +420 284 001 448
E-mail: jmmc2019@guarant.cz




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